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Ketosis in Dairy Cows & Buffaloes
Disease guide CowBuffalo

Ketosis in Dairy Cows & Buffaloes

Ketosis is a shortage of energy in dairy cows and buffaloes, most often in the first weeks after calving, when so much body fat is broken down that ketones build up in the blood. Blood and milk BHB, NEFA, glucose and urine tests help a vet confirm it.

Signs owners may notice

  • A drop in milk yield soon after calving
  • Eating less, often refusing concentrate feed first while still eating some fodder
  • Losing body condition (weight) quickly
  • Dullness and less movement
  • Hard, dry dung
  • A sweet, nail-polish-like smell on the breath or milk
  • In nervous ketosis: licking, constant chewing, circling, staggering or sudden aggression

Signs alone cannot name a disease. If your animal looks unwell, see a veterinarian promptly.

How lab tests help

Blood BHB (beta-hydroxybutyrate) measures the main ketone and is the reference test, while milk BHB is a simpler screen. NEFA shows how much body fat is being broken down, mainly before calving. Glucose is often low, and a urine test can show ketones. A registered veterinarian reads the results with the animal's signs and history.

What is ketosis?

Ketosis, sometimes called acetonaemia, is a metabolic disease of dairy animals. After calving, milk production climbs quickly, and the cow or buffalo often cannot eat enough to meet her energy needs. The body then breaks down its own fat. When fat comes out faster than the liver can handle, ketones build up in the blood. Ketones are acid by-products of fat, and the main one is beta-hydroxybutyrate (BHB).

Ketosis is most common in the first weeks after calving, in high-yielding animals and in animals that were too fat at calving. It often appears with other problems around calving, such as milk fever, a retained afterbirth, uterine infection or a displaced stomach, and any illness that cuts appetite can trigger it. Many animals have raised ketones without clear signs. This is called subclinical ketosis, and it can still lower milk yield and fertility.

Signs to watch for

Common signs include:

  • A drop in milk soon after calving
  • Eating less, often refusing concentrate first
  • Fast loss of body condition
  • Dullness and hard, dry dung
  • A sweet, nail-polish smell on the breath or in the milk

Not every animal shows every sign. Some develop nervous ketosis and may lick objects, chew constantly, walk in circles, stagger or turn aggressive.

Which lab tests help

Beta-hydroxybutyrate (BHB) - Blood Ketones measures BHB in blood and is the reference test for ketosis. The Milk BHB (Ketosis) Test is a simpler screen on fresh milk. The lab report shows the reference range, and your vet decides what a result means for that animal.

NEFA (Non-Esterified Fatty Acids) shows how much body fat is being broken down. It is most useful in the weeks before calving, while BHB is most useful after calving. Glucose Random (RBS) is often low in ketosis, and a Urine Routine can show ketones in urine. For a herd, the Dairy Cow Metabolic Profile typically groups minerals, glucose, ketones, protein and liver tests; the exact list is confirmed when you book. Testing a group of animals around calving can show whether ketosis is a herd problem.

A registered veterinarian interprets every result together with the animal's signs and history. The lab confirms the method, sample needs and reporting time when you book.

When to see your vet

See your vet promptly if a fresh cow or buffalo eats less, drops in milk or loses condition. Nervous signs, such as circling or aggression, need a vet the same day. Your vet will also look for any illness that may have started the ketosis. Ask your vet about prevention for animals close to calving.

Testing in Bhopal

Sample collection is free anywhere in Bhopal, and Pashupatinath Vet Lab is at C-200, C Sector, Shahpura, Bhopal. Dairy farmers in other districts can send samples by courier, by bus parcel or through their local vet, and the lab coordinates by phone or WhatsApp on +91 88175 01118. Reports are shared on WhatsApp, by e-mail and in My Reports on the website.

Lab tests that may help

Common questions

What are the signs of ketosis in cows after calving?
Signs of ketosis in cows after calving include a drop in milk, eating less (often refusing concentrate first), fast weight loss, dullness and hard dung. Some cows have a sweet smell on the breath, and a few show nervous signs such as licking or circling. Many have no clear signs, so testing helps.
Which test is used for ketosis in dairy cows?
Blood BHB is the main test used for ketosis in dairy cows and buffaloes, and milk BHB is a simpler screen. NEFA is used mainly before calving to show fat breakdown, and urine and glucose tests add more detail. A registered veterinarian reads the results with the animal's signs and history.
What is subclinical ketosis?
Subclinical ketosis means ketones are raised in the blood but the animal shows no clear signs. It is common in the first weeks after calving and can still lower milk yield and fertility and make other diseases more likely. Testing several fresh animals with blood or milk BHB can show whether a herd has this problem.
Can buffaloes get ketosis?
Yes, buffaloes can get ketosis, especially high-yielding animals in early lactation, just like dairy cows. The signs and tests are similar: blood BHB, milk BHB, glucose and urine tests. See your vet promptly if a fresh buffalo eats less or drops in milk.

This guide is general information for animal owners. It does not diagnose or treat any animal. A registered veterinarian should examine the animal and read all test results together with its signs and history.

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