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Anaemia in Dogs & Cats (including IMHA)
Disease guide DogCat

Anaemia in Dogs & Cats (including IMHA)

Anaemia means too few red blood cells, so the body gets less oxygen. It can come from blood loss, red cell destruction such as IMHA, or poor production. CBC, PCV, reticulocyte, smear, Coombs and blood parasite tests help your vet find the cause.

Signs owners may notice

  • Pale gums, tongue or inner eyelids
  • Weakness, tiredness and less interest in play or walks
  • Fast breathing or a fast heartbeat
  • Poor appetite
  • Yellow gums, eyes or skin (jaundice)
  • Red, brown or dark urine
  • Black, tarry stools or other signs of bleeding
  • Collapse or fainting

Signs alone cannot name a disease. If your animal looks unwell, see a veterinarian promptly.

How lab tests help

A CBC and PCV show how severe the anaemia is, and a reticulocyte count shows whether the bone marrow is making new red cells. A blood smear shows red cell shapes and parasites. Saline agglutination and Coombs tests help when IMHA is suspected. Iron tests and blood parasite tests look for other causes. A registered veterinarian reads all results with the pet's signs and history.

What is anaemia?

Anaemia means the blood has too few red blood cells, or too little haemoglobin, the red protein that carries oxygen. Without enough oxygen, the body tires easily. Anaemia is a sign of another problem, not a disease on its own.

There are three main causes. Blood can be lost, for example from an injury, bleeding in the gut, or heavy flea, tick or hookworm burdens. Red cells can be destroyed, for example by blood parasites such as Babesia in dogs or Mycoplasma haemofelis in cats, or by poisons such as onion and garlic. Or the bone marrow may not make enough red cells, as in long-term kidney disease, chronic illness or bone marrow disease.

In immune-mediated haemolytic anaemia (IMHA), the immune system attacks the body's own red cells. IMHA can develop quickly and is serious.

Signs to watch for

Common signs include:

  • Pale gums or tongue
  • Weakness and tiredness
  • Fast breathing or a fast heartbeat
  • Poor appetite
  • Yellow gums or eyes
  • Red, brown or dark urine

Mild anaemia may cause few signs, and cats often hide signs until the anaemia is severe.

Which lab tests help

A Complete Blood Count (CBC) or Packed Cell Volume (PCV) shows how severe the anaemia is. A Reticulocyte Count counts young red cells. A high count usually means the bone marrow is responding, which points to blood loss or red cell destruction, while a low count suggests a production problem. After sudden blood loss, this response can take a few days to show.

A General Blood Picture (GBP) looks at red cells on a stained smear, where their shape can give clues. A Blood Protozoa (Blood Parasite Smear) looks for blood parasites, but they can be missed, so your vet may add PCR, such as the Tick Fever Panel RT-PCR (4 Strain: B. gibsoni, B. canis, E. canis & Anaplasma spp.) for dogs or the Haemotropic Mycoplasma (Mycoplasma haemofelis) RT-PCR for cats.

When IMHA is suspected, the Saline Agglutination Test (Auto-agglutination) checks whether red cells clump together, and the Direct Coombs Test (DAT) looks for antibodies stuck to red cells. A negative Coombs test does not rule IMHA out. IMHA can also be triggered by other diseases, which your vet may look for.

Iron and Iron Binding Capacity (TIBC / UIBC) & Transferrin Saturation help when long-term blood loss is suspected, because it can use up the body's iron. If the cause stays unclear, your vet may take a sample for Bone Marrow Aspiration Cytology.

Every result is read by a registered veterinarian, together with your pet's signs and history.

When to see your vet

See your vet promptly if your pet has pale gums, tires easily or seems weak. Very pale or yellow gums, red or dark urine, fast breathing, collapse or any bleeding need a vet the same day.

Testing in Bhopal

Pashupatinath Vet Lab is at C-200, C Sector, Shahpura, Bhopal, with free sample collection anywhere in Bhopal. Owners in other districts can send blood samples by courier or bus parcel, or through their local vet, after a call or WhatsApp message to +91 88175 01118. The lab confirms the method, sample needs and reporting time when you book. Reports are shared on WhatsApp, by e-mail and in My Reports on the website.

Lab tests that may help

Common questions

What causes anaemia in dogs and cats?
Anaemia in dogs and cats has three main causes: blood loss, red cells being destroyed, and the bone marrow not making enough red cells. Examples include fleas, ticks and worms, blood parasites, IMHA, poisons such as onion, and long-term kidney disease. Tests help your vet find which one applies.
What is IMHA in dogs and cats?
IMHA (immune-mediated haemolytic anaemia) is a serious condition in which the immune system attacks the body's own red blood cells. Signs include pale or yellow gums, weakness, fast breathing and dark urine. A CBC, blood smear, saline agglutination and Coombs tests help your vet confirm it. A pet with these signs needs a vet the same day.
What does a reticulocyte count show in a pet's blood test?
A reticulocyte count shows whether the bone marrow is making new red blood cells. A high count usually means the body is replacing lost or destroyed cells, while a low count suggests the marrow is not keeping up. After sudden blood loss, the count can take a few days to rise. Your vet reads it with the CBC.
Can ticks and fleas cause anaemia in pets?
Yes. Heavy flea or tick burdens can cause blood loss, especially in puppies and kittens, and ticks can also pass on blood parasites that destroy red cells. A CBC and blood parasite tests can help your vet find the cause. Ask your vet about flea and tick prevention.

This guide is general information for animal owners. It does not diagnose or treat any animal. A registered veterinarian should examine the animal and read all test results together with its signs and history.

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