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Kidney Disease in Dogs & Cats
Disease guide DogCat

Kidney Disease in Dogs & Cats

Kidney disease means the kidneys cannot filter waste from the blood as well as they should. Blood tests such as creatinine, urea and SDMA, with urine tests such as urine routine and UPC ratio, can help your vet find it early and follow it.

Signs owners may notice

  • Drinking more water and passing more urine
  • Weight loss and a poor or picky appetite
  • Vomiting or bad breath
  • Low energy and a dull, untidy coat
  • Pale gums from anaemia
  • Passing very little or no urine, which is an emergency

Signs alone cannot name a disease. If your animal looks unwell, see a veterinarian promptly.

How lab tests help

Creatinine and urea (BUN) show how well the kidneys clear waste, and SDMA can rise earlier than creatinine. A urine routine shows how well the kidneys concentrate urine and whether protein or blood is present. The UPC ratio and microalbuminuria measure protein loss, and a CBC can show anaemia. A registered veterinarian reads all results with the pet's signs, hydration and history.

What is kidney disease?

The kidneys filter waste out of the blood and pass it out in the urine. They also keep the right balance of water and salts, and help the body make red blood cells. Kidney disease means the kidneys can no longer do this work as well as they should.

There are two main types. Acute kidney injury comes on suddenly, for example after a poison, a severe infection such as leptospirosis, or a blocked bladder. Lilies are very poisonous to cats, and grapes and raisins can harm a dog's kidneys. Chronic kidney disease develops slowly over months or years and is common in older cats and dogs. The kidneys can lose much of their working power before signs appear.

Signs to watch for

Common signs include:

  • Drinking more and passing more urine
  • Weight loss and poor appetite
  • Vomiting or bad breath
  • Low energy and a dull coat
  • Pale gums
  • Passing very little or no urine

Early kidney disease often shows no signs, so routine tests matter in older pets.

Which lab tests help

The Kidney Function Test (KFT) usually includes urea and creatinine, waste products that build up when the kidneys are weak. Both can also rise with dehydration, so your vet reads them with a urine test. Creatinine, Serum can read lower in thin pets with little muscle, which can hide kidney disease.

The SDMA (Symmetric Dimethylarginine) is another marker of how well the kidneys filter. It often rises earlier than creatinine and is less affected by muscle loss.

A Urine Routine shows how concentrated the urine is, and whether it contains protein, blood, sugar or signs of infection. The Urine Protein Creatinine Ratio (UPC Ratio) measures how much protein is leaking into the urine. Microalbuminuria (Urine Albumin) can find very small amounts of albumin, a blood protein, and is read with the UPC ratio.

A Complete Blood Count (CBC) can show anaemia, and Phosphorus and Electrolytes, Serum (Na, K & Cl) check minerals and salts that kidney disease can upset. If infection is possible, your vet may add a Urine Culture & Sensitivity. The Comprehensive Vital Panel combines kidney and liver tests with a blood count and sugar.

A registered veterinarian reads each result alongside your pet's signs, hydration and history, and may repeat tests over time to see how the kidneys are changing.

When to see your vet

See your vet promptly if your pet drinks or urinates more, loses weight or vomits. A pet that stops passing urine, collapses, or may have eaten lilies, grapes, raisins or another poison needs a vet the same day. Ask your vet how often an older pet should have kidney tests.

Testing in Bhopal

Pashupatinath Vet Lab is at C-200, C Sector, Shahpura, Bhopal, and collects samples free anywhere in Bhopal. If you live in another district, send samples by courier, by bus parcel or through your local vet, and call or WhatsApp +91 88175 01118 to plan it. The lab confirms the method, sample needs and reporting time when you book. Reports come on WhatsApp, by e-mail and in My Reports on the website.

Lab tests that may help

Packages

Full liver and kidney function with blood count and sugar.

  • CBC
  • KFT
  • + 3 more tests

₹1,800

Save ₹530 ₹2,330

Common questions

What blood test shows kidney problems in dogs and cats?
The main blood tests for kidney problems are creatinine, urea (BUN) and SDMA, often done together as a kidney function test (KFT). SDMA can rise earlier than creatinine. Vets read them with a urine routine and UPC ratio, because dehydration can also raise urea and creatinine.
What is an SDMA test and why does my vet want it?
SDMA is a substance that healthy kidneys filter out of the blood. It often rises earlier than creatinine when the kidneys start to fail, and muscle loss affects it less, which helps in thin or older pets. A registered veterinarian reads SDMA together with creatinine, urine tests and your pet's signs.
Why does my vet need a urine sample for kidney disease?
A urine sample shows things blood tests cannot: how well the kidneys concentrate urine, whether protein is leaking, and signs of infection or blood. The UPC ratio measures protein loss. Your vet may ask for fresh urine in a clean container, or collect it straight from the bladder.
Can kidney disease in cats and dogs be found before signs show?
Yes, routine blood and urine tests can often find kidney changes before a pet looks unwell. SDMA, creatinine, urine concentration and the UPC ratio are commonly used for this. Ask your vet how often your pet should be checked, especially as it gets older.

This guide is general information for animal owners. It does not diagnose or treat any animal. A registered veterinarian should examine the animal and read all test results together with its signs and history.

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