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SPEP

Serum Protein Electrophoresis (SPEP)

Serum protein electrophoresis (SPEP) separates blood proteins into albumin and several globulin groups and shows them as a pattern. It can help a vet look into high protein, long-term infection and some blood cancers in dogs and cats.

Sample
Serum (plain)
Quantity
As advised
Report
Confirmed when you book
Collection
Free in Bhopal

What this test checks

  • Albumin, the main protein made by the liver
  • The globulin groups (alpha, beta and gamma), which include antibodies
  • Whether a globulin rise is broad or a narrow single spike

When your vet may advise it

  • When a routine test shows high total protein or globulin without a clear cause
  • Suspected long-term infection, such as tick fever in dogs or FIP in cats
  • When a blood cancer such as multiple myeloma is suspected

About this test

Blood serum contains albumin and many globulins, a group of proteins that includes antibodies. In SPEP, an electric current separates these proteins, and the result is shown as a graph of peaks. A broad rise in the antibody area often goes with long-term inflammation or infection, such as tick fever in dogs or FIP (feline infectious peritonitis) in cats. A narrow, tall spike can point to a blood cancer such as multiple myeloma, though some infections can cause one too. The pattern needs expert reading, so a pathologist or registered veterinarian interprets it with your pet's signs, history and other tests.

How to prepare

A plain serum sample is needed, and a recent total protein, albumin and globulin result helps the reading. The lab confirms the method, sample needs and reporting time when you book.

Questions about SPEP

What does a spike on SPEP mean in a dog?
A narrow spike usually means one family of antibody-making cells is producing a large amount of one antibody. It can point to a blood cancer such as multiple myeloma or lymphoma, but some infections, including tick fever, can also cause it. Your vet decides which further tests are needed.
Can SPEP help diagnose FIP in a cat?
It can support, but not confirm, a suspicion of FIP. Many cats with FIP have high globulins with a broad rise on SPEP, but other long-term infections and inflammation can look similar. A registered veterinarian combines it with the cat's signs and other tests.

Before you book this test

Why this notice: so you know, before you book, how a test is done, what its limits are and who is responsible.

  • Where it is tested. Some tests are done wholly or partly by an independent partner laboratory. The lab tells you before booking if this test is sent out, and the report names the laboratory that did it.
  • What a result can and cannot tell you. No test is right every time. A normal result does not rule out every disease, and an abnormal result does not prove one. A registered veterinarian should read the report with the animal’s signs and history before any treatment is started, changed or stopped.
  • The sample. A sample that is clotted, too small, wrongly labelled, leaking or too old may be rejected or reported with a note, and the lab may ask for a fresh one.
  • Reporting time. Confirmed when you book. Times are estimates, not guarantees, and the lab confirms the time when you book.
  • Emergencies. A booking or a pending report must not delay urgent care. If an animal has collapsed, struggles to breathe, has fits or bleeds heavily, call a veterinarian at once.

Please read our Terms of Service, Medical Disclaimer, Privacy Policy and Refund and Cancellation Policy. Pashupatinath Vet Lab is operated by Duaji Healthcare and Tech Private Limited. This page is general information and does not replace a veterinarian’s advice.

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SPEP: Bhopal and the big cities of Madhya Pradesh

Free sample collection anywhere in Bhopal. From the other cities, send the sample by courier, bus parcel or through your local veterinarian, and the report comes to you online.

Free collection in these Bhopal areas

SPEP

Price on request

Ready to get your animal tested?

Book online in two minutes. We collect the sample free of charge anywhere in Bhopal, or you can send it from any district of Madhya Pradesh.

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