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Protein Total, Albumin, Globulin

Protein Total, Albumin, Globulin

This blood test measures total protein and its two main parts, albumin and globulin. It can help show liver, kidney or gut problems, dehydration and long-lasting inflammation in dogs, cats, cows and buffaloes.

Sample
Serum (plain)
Quantity
2 mL
Report
Same day to 24 hours
Collection
Free in Bhopal

What this test checks

  • Total protein in the serum
  • Albumin, the main protein made by the liver
  • Globulin, which includes antibodies
  • Albumin to globulin (A:G) ratio, worked out from the two values

Benefits of this test

  • Gives total protein, albumin and globulin from one serum sample.
  • Shows whether a protein change is in albumin, globulin or both, which a total value alone cannot show.
  • Can help your vet spot protein loss, liver trouble or long-running inflammation that is not obvious from the outside.
  • Helps judge hydration and nutrition, and can be repeated to follow an illness over time.
  • A routine blood test, normally reported the same day or within 24 hours.

When your vet may advise it

  • Swelling of the legs or belly, or under the jaw in a cow or buffalo.
  • Weight loss, poor appetite or a dull coat with no clear reason.
  • Diarrhoea or vomiting that goes on for a long time.
  • A cow or buffalo that is weak and losing condition, especially where worms or liver fluke are a problem.
  • A newborn calf in its first days, to help check that it got enough colostrum (first milk).
  • Yellow gums or eyes, or other signs that suggest a liver problem.

About this test

Proteins are the building blocks that keep blood and body tissues working. This test measures total protein and then splits it into its two main groups. Albumin is made by the liver. It holds fluid inside the blood vessels and carries many substances around the body. Globulins include the antibodies that fight germs, so they often rise when the body is dealing with a long infection or inflammation.

The test is done on serum, the clear liquid that separates from clotted blood. A machine measures total protein and albumin. Globulin is usually worked out by taking albumin away from the total. Vets then look at the albumin to globulin ratio, called the A:G ratio. Many things can change these numbers. They include liver disease, protein loss through the kidneys or gut, heavy worm or liver fluke infection, dehydration and long-term inflammation. Each one changes the pattern in its own way.

It is a useful first look, but it does not name a disease by itself. The numbers make sense only when read with the animal's signs and other tests.

How to prepare

For dogs and cats, many vets prefer 8 to 12 hours without food before the blood is drawn, and water is fine; for cows and buffaloes, follow your vet's advice. Blood goes into a plain tube and the serum is tested at the lab. Sample collection is free anywhere in Bhopal; from other places, the serum can go by courier, bus parcel or through your vet after you call the lab.

Reading the result

A change in total protein, albumin or globulin is a clue, not a diagnosis. A registered veterinarian reads the values together with your animal's signs, history and other test results.

Questions about Protein Total, Albumin, Globulin

What does a low albumin level mean?
Low albumin means the blood holds less of the main protein made by the liver. It can happen with liver disease, protein loss through the kidneys or gut, heavy worm infection, a long illness or poor feeding. Your vet finds the cause using other tests and the animal's signs.
How is this different from a Protein Total test alone?
A Protein Total test gives one number for all the proteins together. This test also splits it into albumin and globulin, so your vet can see which group has changed. That usually gives more clues than a single total.
Can dehydration change the result?
Yes. When an animal is dehydrated, the blood is more concentrated, so protein values can look higher than they really are. Tell your vet about vomiting, diarrhoea, poor drinking or heat stress so that the numbers are read correctly.
What is the albumin to globulin (A:G) ratio?
The A:G ratio compares albumin with globulin. When it goes up or down, your vet can tell which of the two proteins has changed more. It helps narrow down the possible causes, but it cannot name a disease on its own.

Before you book this test

Why this notice: so you know, before you book, how a test is done, what its limits are and who is responsible.

  • Where it is tested. Some tests are done wholly or partly by an independent partner laboratory. The lab tells you before booking if this test is sent out, and the report names the laboratory that did it.
  • What a result can and cannot tell you. No test is right every time. A normal result does not rule out every disease, and an abnormal result does not prove one. A registered veterinarian should read the report with the animal’s signs and history before any treatment is started, changed or stopped.
  • The sample. A sample that is clotted, too small, wrongly labelled, leaking or too old may be rejected or reported with a note, and the lab may ask for a fresh one.
  • Reporting time. Same day to 24 hours. Times are estimates, not guarantees, and the lab confirms the time when you book.
  • Emergencies. A booking or a pending report must not delay urgent care. If an animal has collapsed, struggles to breathe, has fits or bleeds heavily, call a veterinarian at once.

Please read our Terms of Service, Medical Disclaimer, Privacy Policy and Refund and Cancellation Policy. Pashupatinath Vet Lab is operated by Duaji Healthcare and Tech Private Limited. This page is general information and does not replace a veterinarian’s advice.

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